Guido Sant'Anna was born in Sao Paulo, Brazil. He began to study violin at 5 years old, with the help of his mother and brothers, who were also learning violin. Shortly thereafter, he started taking lessons with the violin teacher Marcia Uhlemann, from the Fukuda Institute. Guido was a part of the Kodomo ensemble from 2010 to 2013. At seven years old Guido's talent was discovered among the participants of Kodomo by maestro Julio Medaglia. The conductor took him to his first soloist concerts accompanied by the chamber orchestra. In 2013, after many difficulties, he got financial aid from a group of friends and started taking lessons with teacher Elisa Fukuda. He got a scholarship from Fundagao Magda Tagliaferro, after that, he was sponsored by Cultura Artistica. Guido has performed as a soloist in Brazil and abroad. In April 2018 he was the first Brazilian to be selected to participate in the Menuhin Competition. He won the 6th place among more than 300 excellent competitors. Since 2018 Guido has joined The Perlman Music Program, participating in its summer courses. Today Guido still studies with teacher Elisa Fukuda, and he plays the 1833 Iorio Violin, kindly loaned by the Caris Foundation.
Finalist at the TV Show Classical Brazilian Music Competition "Preludio" (2014), the XVI National Strings Concourse Paulo Bosisio (II prize, 2015), the Yehudi Menuhin International Competition for Young Violinists (VI prize, Audience prize and the Chamber Music Prize, 2018, Switzerland); Young Talent Award of the Concerto Magazine (I prize, 2018), at "Jovens Solistas" competition the Symphonic Orchestra of Sao Paulo (I prize, 2021 ), at the Astana Violin Competition in Astana, Kazakhstan (I prize, 2021 ).
Guido performed with such groups as Johann Sebastian Rio at Theatro Municipal do Rio de Janeiro, at Unasp Engenheiro Coelho (conductor Jetro Meira de Oliveira), Camerata Sesi on Vitoria (conductor Leonardo David), UFRN Symphony Orchestra on Natal (cConductor Andre Muniz), Camerata UFMT em Cordas on Cuiaba (conductor Oliver Yatsugafu), ULBRA Chamber Orchestra on Porto Alegre (conductor Tiago Flores), Symphony Orchestra of Sao Paulo on Sao Paulo (conductor Jose Maria Florencio), Symphony Orchestra of Bahia on Salvador ( conductor Erick Vasconcelos), Symphony Orchestra of Parana on Curitiba (conductor Carlos Prazeres), Camerata Fukuda on Sao Paulo (conductor Celso Antunes).